Amlodipine tablets: from what help and under what pressure to take them?

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50-60% of the world’s inhabitants are diagnosed with hypertension after the age of 60 years. But the younger generation (up to 40 years old) is addressing complaints of blood pressure to therapists more and more often. The reasons for the occurrence of the disease are many: smoking, alcohol, sedentary lifestyle, etc. Doctors prescribe medications that lower blood pressure during treatment. Most often, their choice is Amlodipine, from what and how to apply it you will learn in our article.

Amlodipine-blood-pressure

Amlodipine: from what helps?

The drug affects the body in two ways: antianginal and hypotensive. The composition of the drug: amlodipine besylate, crospovidone, lactose monohydrate, povidone, calcium stearate. Available in the form of tablets of 5 and 10 mg.

Antianginal effect is the ability to stop, effectively prevent strokes by normalizing the work of the heart muscle, improving coronary blood flow. Hypotensive effect is a decrease in blood pressure by expanding the diameter of blood vessels, relieving spasms, leading to their narrowing.

The action of the drug is based on blocking slow calcium channels. Due to this, the transition of calcium ions to the structural elements of smooth muscle vessels is spiked. With an increase in the total amount of calcium ions, the muscles of the vessels decrease in size, the passage for the blood flow narrows, respectively, the blood pressure rises. The drug prevents the increase in vascular resistance, thickening of the walls of blood ducts, due to this, blood pressure is reduced. Hypotensive effect due to the control of the state of vascular smooth muscle. The length of the cells of the smooth muscle vessels increases, the lumen expands, the blood flows faster due to a decrease in duct resistance. Blood pressure decreases, the effect lasts for at least a day. Antianginal effects on the body occurs due to an increase in the patency of arteries and arterioles. The load on the heart decreases, the myocardium receives enough oxygen. This is especially important for angina and ischemia. The risk of coronary artery spasm is reduced. Ischemic heart disease requires special attention to blood pressure indicators. Amplodipine helps to reduce the degree of myocardial hypertrophy, cardioprotectrono and antiatherosclerotic effect on the vessels. The cardioprotective effect on the myocardium is due to the efficient delivery of oxygen and a decrease in the load on the heart. The action of the drug facilitates the condition of patients not only with coronary artery disease, but also its chronic form, reduces the risk of blood clots in atherosclerosis. Amplodipine does not violate the metabolism, so it is used to treat high blood pressure in asthmatics and diabetics. When receiving a daily dose of Amlodipine, patients with vasospastic angina pectoris noted a decrease in the need for nitroglycerin and other nitrates, a decrease in the number of seizures.

Indications for use

Amlodipine has a wide and effective use in the presence of the following diseases:

  • stenocardia;
  • vasospasm;
  • coronary heart disease;
  • non-ischemic cardiomyopathy;
  • bronchial asthma;
  • arterial hypertension;
  • angina of exertion.
Stop taking Amlodipine sharply impossible. Follow the jump and increase in blood pressure, increase the pulse. Dosage should be reduced within a few days.

Instructions.

In appointing the drug, therapists focus on the chronic diseases of patients, the clinical picture as a whole, age, weight.

Amlodipine for pressure and angina is administered in a dose of 5 mg. The amount of the drug is increased, depending on the patient’s condition, the tolerance of the active substance, but not more than 4 times for a single use.

There are several drug regimens: for hypertension, 2.5 to 5 mg daily is prescribed. Reception is single. At what pressure to take the drug, is decided by the doctor together with the patient. The best indicator is 140 -150 mm Hg. v .; For patients with impaired liver function, a separate regimen has been drawn up. As a sample, a dose of 5 mg is assigned, it is possible to increase to 10 mg with a positive result of the medication; in angina pectoris Amlodipine is prophylactic or therapeutic. With the prevention of 10 mg per day, in connection with the attacks and their treatment 5-10 mg; antianginal daily dose is 5 mg in patients of any age. Assigning the drug simultaneously with ACE inhibitors, diuretics, blockers, leave the dosage in the range of 5-10 mg.

It is impossible to arrest a sharp surge in pressure with this medicine. It is taken for prophylactic purposes in chronic diseases of the cardiovascular system, therapeutic – in the detection of coronary artery disease, hypertension. Separately, you should talk about overdose.
With self-dose increase and admission several times a day will require hospitalization of the patient. In the walls of the clinic, gastric lavage is performed, with the help of calcium gluconate, Dopamine, the heart and blood vessels are restored. For home remedy of dosage symptoms, use plentiful drink, vomiting, taking activated charcoal (1 tablet per 10 kg of weight). If the condition does not improve, call the emergency room. Patients with a weight of less than 40 kg and a low growth should be given a daily dose of Amlodipine not more than 2.5 mg.

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Side Effects

Any medication has side effects. Amlodipine tablets are no exception.

Common effects of taking medication for hypertension include:

  1. heart palpitations, shortness of breath;
  2. lowering the pressure to the minimum;
  3. fainting;
  4. swelling of the face;
  5. flushing to the skin of the face;
  6. asthenia;
  7. vasculitis;
  8. migraine,
  9. irregular heartbeat – are rare;
  10. headaches;
  11. drowsiness;
  12. dizziness;
  13. rapid fatigability even with slight physical exertion;
  14. depression, sleep disturbances are rare, occur in 1 out of a thousand patients;
  15. nervousness;
  16. anxiety;
  17. excessive sweating;
  18. nausea, vomiting;
  19. stomach pains;
  20. rarely, dry mouth, diarrhea or constipation, enlarged liver, bloating;
  21. pain when urinating;
  22. skin allergic reactions (itching, rash);
  23. impotence;
  24. decreased libido;
  25. angioedema;
  26. arthrosis;
  27. myalgia;
  28. arthralgia;
  29. rarely – myasthenia gravis;
  30. dermatitis, alopecia;
  31. rhinitis;
  32. convulsions;
  33. reduced vision;
  34. chills;
  35. tinnitus;
  36. lower back pain;
  37. nosebleeds.
In identifying the side effects of the drug on the patient’s body, the doctor selects Amlodipine analogues. This may be Biocom, Amplodin Farmak, etc.

During treatment, changes in the patient’s weight should be monitored. One of the side properties is the reduction or slight hanging of the patient’s body weight. It is necessary to adjust the diet and the amount of salt consumed. Amlodipine causes gum hyperplasia (the tissues of the oral cavity expand, cover the teeth). It is regularly visited by the dentist.

IT IS IMPORTANT TO KNOW! Shocking statistics! Hypertension is the most common disease of the cardiovascular system. With age, the prevalence of the disease increases and reaches 50-65%. In order not to bring to the complications and operations it is important to prevent the disease.

Contraindications

Caution should be taken when taking the drug in children under 16-18 years old, with myocardial infarction, arterial hypotension, aortic stenosis, mitral stenosis. Contraindications include: pregnancy and breastfeeding. Women of childbearing age should avoid unprotected sexual intercourse during treatment with Amlodipine, because its reception causes enormous harm to the development of the fetus during pregnancy. The active ingredient of the drug penetrates into breast milk, therefore, when prescribing a nursing mother, the child is transferred to artificial mixtures; cardiogenic shock; sensitivity to the components of the drug; unstable angina. In the presence of contraindications Amlodipine replaced by analogues. With caution apply the considered drug to people engaged in hazardous labor, requiring concentration of attention, working with technical devices and mechanisms, driving a car. This is due to the fact that at the initial stage of treatment in half of the patients the drug causes drowsiness, lethargy. The use of Amlodipine in type 2 diabetes does not affect the increase in blood glucose levels. Diabetics take it in the usual way.